DOI: https://doi.org/10.52379/mcs.v10.662

Factors Associated with the Persistence of High-Risk Behaviors in Trans Women in Paraguay, 2020 to 2023

Authors

  • Gloria Aguilar Ministerio de Salud Pública y Bienestar Social, Instituto Nacional de Salud, Asunción, Paraguay , Universidad Sudamericana, Facultad de Ciencias de la Salud, Pedro Juan Caballero, Paraguay
  • Liliana Gimenez Ministerio de Salud Pública y Bienestar Social, Instituto Nacional de Salud, Asunción, Paraguay , Ministerio de Salud Pública y Bienestar Social, Programa Nacional de Lucha contra el VIH/Sida (PRONASIDA), Asunción, Paraguay
  • Carlos Miguel Rios-González Ministerio de Salud Pública y Bienestar Social, Instituto Nacional de Salud, Asunción, Paraguay , Universidad Sudamericana, Facultad de Ciencias de la Salud, Pedro Juan Caballero, Paraguay https://orcid.org/0000-0001-7558-8206
  • Maria Isabel Rodriguez-Riveros Universidad Sudamericana, Facultad de Ciencias de la Salud, Pedro Juan Caballero, Paraguay
  • Elena María Candia Florentín Ministerio de Salud Pública y Bienestar Social, Programa Nacional de Lucha contra el VIH/Sida (PRONASIDA), Asunción, Paraguay

Abstract

Introduction: Trans women continue to be one of the most vulnerable populations to HIV in Paraguay, due to multiple individual, social, and structural factors that determine the persistence of high-risk sexual behaviors. Despite prevention efforts, significant gaps persist that impede an effective and inclusive response. Objective: To analyze the factors associated with the persistence of high-risk behaviors for HIV infection in trans women in Paraguay during the period 2020 to 2023. Methodology: An observational, analytical, retrospective cohort study with a quantitative approach. One hundred and fifty-four trans women participated in two measurements (2020 and 2023) in the regions of Asunción, Central, and Alto Paraná. The persistence of risk behaviors was analyzed, defined as the continuation of at least one practice (unprotected anal sex, sex work, or drug use). Descriptive and bivariate analyses were performed. The significance level was set at p < 0.05. Results: The persistence of risk behaviors was 61.04%. Significant associations were observed with age (greater persistence between 20 and 39 years of age), department of residence (higher in Alto Paraná), and the presence of depressive symptoms (p = 0.002). No significant differences were found regarding educational level, HIV knowledge, or risk perception. Conclusion: The persistence of risk behaviors in trans women is influenced by structural, territorial, and mental health factors. Current prevention strategies should be strengthened through an intersectoral, territorially sensitive approach with a strong component in mental health and social inclusion.

Keywords:

Risk behaviors, HIV, Transgender, Paraguay

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References

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Article history

Received

Accepted

Published

10/14/2026

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Section

Original Articles

How to Cite

1.
Aguilar G, Gimenez L, Rios-González CM, Rodriguez-Riveros MI, Candia Florentín EM. Factors Associated with the Persistence of High-Risk Behaviors in Trans Women in Paraguay, 2020 to 2023. Med Clín Soc. 2026;10(1):e662. doi:10.52379/mcs.v10.662